AirHint found the following cheapest one-way flights from Ancona (AOI) to Madrid (MAD) in December 2025 (see full year).
One-Way flights
| 22 Dec | Volotea | direct | |
| 19 Dec | Volotea | direct | |
| 26 Dec | Volotea | direct | |
| 15 Dec | Volotea | ||
| 16 Dec | Ryanair | ||
| 13 Dec | Ryanair | ||
| 14 Dec | Wizz Air Malta | ||
| 17 Dec | Wizz Air Malta | ||
| 21 Dec | Wizz Air Malta | ||
| 24 Dec | DAT |
Also check the deals for return flights from Ancona to Madrid in December.
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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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