Cheapest one-way flights from Atlanta to Santiago in December from $228

AirHint found the following cheapest one-way flights from Atlanta (ATL) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

01 Dec Frontier Airlines
28 Dec Spirit Airlines
11 Dec Spirit Airlines
13 Dec Spirit Airlines
22 Dec Frontier Airlines
23 Dec Spirit Airlines
18 Dec Spirit Airlines
01 Dec LATAM Airlines Group direct
11 Dec Delta direct
13 Dec Delta direct

Also check the deals for return flights from Atlanta to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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