AirHint found the following cheapest one-way flights from Cairo (CAI) to Johannesburg (JNB) in December 2025 (see full year).

One-Way flights

03 Dec	Qatar Airways
04 Dec	Qatar Airways
07 Dec	Qatar Airways
27 Dec	Qatar Airways
07 Dec	EgyptAir	direct
10 Dec	Qatar Airways
11 Dec	Qatar Airways
04 Dec	EgyptAir	direct
11 Dec	EgyptAir	direct
21 Dec	EgyptAir	direct

Also check the deals for return flights from Cairo to Johannesburg in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Cairo to Johannesburg in December from $334

One-Way flights