Cheapest one-way flights from Charlotte to Rome in October from $172

AirHint found the following cheapest one-way flights from Charlotte (CLT) to Rome (FCO) in October 2025 (see full year).

One-Way flights

14 Oct Spirit Airlines
17 Oct Spirit Airlines
14 Oct American Airlines direct
06 Oct United
08 Oct United
07 Oct Lufthansa
17 Oct British Airways direct
06 Oct American Airlines direct
07 Oct American Airlines direct
08 Oct American Airlines direct

Also check the deals for return flights from Charlotte to Rome in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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