Cheapest one-way flights from Charlotte to Rome in April from $221

AirHint found the following cheapest one-way flights from Charlotte (CLT) to Rome (FCO) in April 2026 (see full year).

One-Way flights

27 Apr Frontier Airlines
20 Apr Frontier Airlines
24 Apr Spirit Airlines
02 Apr Frontier Airlines
10 Apr Spirit Airlines
20 Apr American Airlines direct
24 Apr American Airlines direct
27 Apr American Airlines direct
08 Apr United
08 Apr American Airlines direct

Also check the deals for return flights from Charlotte to Rome in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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