Cheapest one-way flights from Charlotte to Madrid in September from $203

AirHint found the following cheapest one-way flights from Charlotte (CLT) to Madrid (MAD) in September 2025 (see full year).

One-Way flights

27 Sep Spirit Airlines
23 Sep Spirit Airlines
25 Sep Spirit Airlines
10 Sep Spirit Airlines
13 Sep Spirit Airlines
02 Sep Spirit Airlines
12 Sep Spirit Airlines
23 Sep American Airlines direct
27 Sep British Airways direct
25 Sep American Airlines direct

Also check the deals for return flights from Charlotte to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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