AirHint found the following cheapest one-way flights from Catania (CTA) to Prague (PRG) in September 2025 (see full year).

One-Way flights

09 Sep	Wizz Air Malta	direct
05 Sep	Ryanair	direct
24 Sep	Aeroitalia
02 Sep	Wizz Air Malta	direct
16 Sep	Ryanair
17 Sep	Ryanair
20 Sep	Wizz Air Malta	direct
30 Sep	Wizz Air Malta	direct
26 Sep	easyJet
29 Sep	easyJet

Also check the deals for return flights from Catania to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Catania to Prague in September from $46

One-Way flights