AirHint found the following cheapest one-way flights from Cartagena (CTG) to Madrid (MAD) in August 2025 (see full year).

One-Way flights

06 Aug	Plus Ultra Lineas Aereas	direct
07 Aug	Plus Ultra Lineas Aereas	direct
19 Aug	Spirit Airlines
04 Aug	Plus Ultra Lineas Aereas	direct
18 Aug	Arajet
02 Aug	Spirit Airlines
12 Aug	JetSmart
16 Aug	JetSmart
17 Aug	Avianca
01 Aug	Spirit Airlines

Also check the deals for return flights from Cartagena to Madrid in August.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Cartagena to Madrid in August from $436

One-Way flights