AirHint found the following cheapest one-way flights from Cuzco (CUZ) to Santiago (SCL) in February 2026 (see full year).

One-Way flights

03 Feb	JetSmart
27 Feb	JetSmart
09 Feb	Sky Airline
04 Feb	Sky Airline
07 Feb	Sky Airline
25 Feb	JetSmart
04 Feb	LATAM Airlines Group	direct
07 Feb	LATAM Airlines Group	direct
03 Feb	LATAM Airlines Group	direct
10 Feb	LATAM Airlines Group	direct

Also check the deals for return flights from Cuzco to Santiago in February.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Cuzco to Santiago in February from $112

One-Way flights