Cheapest one-way flights from Denver to Chicago in October from $52

AirHint found the following cheapest one-way flights from Denver (DEN) to Chicago (ORD) in October 2025 (see full year).

One-Way flights

02 Oct Frontier Airlines direct
03 Oct Frontier Airlines direct
22 Oct American Airlines direct
28 Oct Southwest Airlines direct
07 Oct American Airlines direct
08 Oct American Airlines direct
09 Oct Frontier Airlines direct
06 Oct American Airlines direct
14 Oct United direct
05 Oct American Airlines direct

Also check the deals for return flights from Denver to Chicago in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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