Cheapest one-way flights from Denver to Chicago in September from $54

AirHint found the following cheapest one-way flights from Denver (DEN) to Chicago (ORD) in September 2025 (see full year).

One-Way flights

06 Sep Frontier Airlines direct
07 Sep Frontier Airlines direct
22 Sep American Airlines direct
15 Sep American Airlines direct
09 Sep American Airlines direct
03 Sep American Airlines direct
04 Sep American Airlines direct
28 Sep American Airlines direct
26 Sep Southwest Airlines direct
05 Sep American Airlines direct

Also check the deals for return flights from Denver to Chicago in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Chicago

Cheap car rent in Chicago

Feel free to contact us with any feedback or request another flight research.