Cheapest one-way flights from Denver to San Diego in April from $112

AirHint found the following cheapest one-way flights from Denver (DEN) to San Diego (SAN) in April 2026 (see full year).

One-Way flights

22 Apr Alaska Airlines direct
25 Apr Alaska Airlines direct
19 Apr Alaska Airlines direct
24 Apr Alaska Airlines direct
26 Apr Alaska Airlines direct

Also check the deals for return flights from Denver to San Diego in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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