Cheapest one-way flights from Detroit to Rome in October from $194

AirHint found the following cheapest one-way flights from Detroit (DTW) to Rome (FCO) in October 2025 (see full year).

One-Way flights

18 Oct Spirit Airlines
20 Oct Spirit Airlines
14 Oct Spirit Airlines
07 Oct Spirit Airlines
11 Oct Spirit Airlines
01 Oct Spirit Airlines
19 Oct jetBlue
03 Oct Spirit Airlines
14 Oct Air France direct
19 Oct Air France direct

Also check the deals for return flights from Detroit to Rome in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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