Cheapest one-way flights from Detroit to Rome in May from $389

AirHint found the following cheapest one-way flights from Detroit (DTW) to Rome (FCO) in May 2026 (see full year).

One-Way flights

27 May WestJet
25 May WestJet
28 May Spirit Airlines
31 May WestJet
29 May WestJet
14 May Delta direct
25 May Air France direct
27 May Air France direct
31 May Air France direct
29 May Air France direct

Also check the deals for return flights from Detroit to Rome in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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