AirHint found the following cheapest one-way flights from Detroit (DTW) to Rome (FCO) in May 2026 (see full year).

One-Way flights

15 May	jetBlue
28 May	TAP
15 May	Air France	direct
28 May	Air France	direct

Also check the deals for return flights from Detroit to Rome in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Detroit to Rome in May from $429

One-Way flights