Cheapest one-way flights from Detroit to Sao Paulo in December from $216

AirHint found the following cheapest one-way flights from Detroit (DTW) to Sao Paulo (GRU) in December 2025 (see full year).

One-Way flights

08 Dec Frontier Airlines
03 Dec Spirit Airlines
09 Dec Spirit Airlines
07 Dec Spirit Airlines
10 Dec Spirit Airlines
01 Dec Spirit Airlines
13 Dec Spirit Airlines
11 Dec Spirit Airlines
15 Dec Spirit Airlines
06 Dec Spirit Airlines

Also check the deals for return flights from Detroit to Sao Paulo in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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