Cheapest one-way flights from Detroit to Sao Paulo in May from $611

AirHint found the following cheapest one-way flights from Detroit (DTW) to Sao Paulo (GRU) in May 2026 (see full year).

One-Way flights

11 May LATAM Airlines Group
05 May LATAM Airlines Group
20 May LATAM Airlines Group
08 May LATAM Airlines Group
26 May LATAM Airlines Group
17 May LATAM Airlines Group
23 May LATAM Airlines Group
29 May LATAM Airlines Group
02 May LATAM Airlines Group

Also check the deals for return flights from Detroit to Sao Paulo in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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