AirHint found the following cheapest one-way flights from Detroit (DTW) to Islamabad (ISB) in December 2025 (see full year).
One-Way flights
| 30 Dec | Spirit Airlines | ||
| 08 Dec | Spirit Airlines | ||
| 07 Dec | Spirit Airlines | ||
| 22 Dec | Frontier Airlines | ||
| 17 Dec | Spirit Airlines | ||
| 13 Dec | Etihad Airways |
Also check the deals for return flights from Detroit to Islamabad in December.
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