Cheapest one-way flights from Detroit to Istanbul in October from $217

AirHint found the following cheapest one-way flights from Detroit (DTW) to Istanbul (IST) in October 2025 (see full year).

One-Way flights

08 Oct Spirit Airlines
01 Oct Spirit Airlines
07 Oct Spirit Airlines
02 Oct Spirit Airlines
19 Oct Spirit Airlines
13 Oct Spirit Airlines
26 Oct Spirit Airlines
03 Oct Spirit Airlines
08 Oct Turkish Airlines direct
01 Oct Turkish Airlines direct

Also check the deals for return flights from Detroit to Istanbul in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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