Cheapest one-way flights from Detroit to Istanbul in May from $309

AirHint found the following cheapest one-way flights from Detroit (DTW) to Istanbul (IST) in May 2026 (see full year).

One-Way flights

02 May Spirit Airlines
09 May Spirit Airlines
08 May Spirit Airlines
01 May Spirit Airlines
03 May Spirit Airlines
23 May WestJet
04 May Lufthansa
03 May Turkish Airlines direct
04 May Turkish Airlines direct
08 May Turkish Airlines direct

Also check the deals for return flights from Detroit to Istanbul in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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