Cheapest one-way flights from Detroit to Santo Domingo in December from $157

AirHint found the following cheapest one-way flights from Detroit (DTW) to Santo Domingo (SDQ) in December 2025 (see full year).

One-Way flights

31 Dec Spirit Airlines
22 Dec Frontier Airlines
18 Dec Spirit Airlines
17 Dec Spirit Airlines
21 Dec Frontier Airlines
24 Dec Spirit Airlines
25 Dec Spirit Airlines
11 Dec Spirit Airlines
12 Dec Spirit Airlines
15 Dec Spirit Airlines

Also check the deals for return flights from Detroit to Santo Domingo in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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