Cheapest one-way flights from Newark to Santiago in December from $248

AirHint found the following cheapest one-way flights from Newark (EWR) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

05 Dec Spirit Airlines
06 Dec Spirit Airlines
09 Dec jetBlue
03 Dec Spirit Airlines
04 Dec Spirit Airlines
07 Dec Spirit Airlines
16 Dec Spirit Airlines
01 Dec Spirit Airlines
24 Dec Spirit Airlines
17 Dec Spirit Airlines

Also check the deals for return flights from Newark to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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