Cheapest one-way flights from Rome to Santander in December from $78

AirHint found the following cheapest one-way flights from Rome (FCO) to Santander (SDR) in December 2025 (see full year).

One-Way flights

07 Dec Vueling Airlines
26 Dec Vueling Airlines

Also check the deals for return flights from Rome to Santander in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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