Cheapest one-way flights from Sao Paulo to Santiago in October from $80

AirHint found the following cheapest one-way flights from Sao Paulo (GRU) to Santiago (SCL) in October 2025 (see full year).

One-Way flights

29 Oct Sky Airline direct
03 Oct Sky Airline direct
09 Oct LATAM Airlines Group direct
25 Oct LATAM Airlines Group direct
27 Oct LATAM Airlines Group direct
15 Oct Aerolineas Argentinas
10 Oct Aerolineas Argentinas
12 Oct LATAM Airlines Group
02 Oct LATAM Airlines Group
08 Oct LATAM Airlines Group

Also check the deals for return flights from Sao Paulo to Santiago in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago

Feel free to contact us with any feedback or request another flight research.