AirHint found the following cheapest one-way flights from Guatemala City (GUA) to Houston (IAH) in October 2025 (see full year).

One-Way flights

29 Oct	Spirit Airlines
18 Oct	Spirit Airlines
01 Oct	Spirit Airlines
04 Oct	Spirit Airlines
28 Oct	Avianca
14 Oct	Spirit Airlines
19 Oct	Spirit Airlines
31 Oct	Spirit Airlines
03 Oct	Spirit Airlines
28 Oct	United	direct

Also check the deals for return flights from Guatemala City to Houston in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Guatemala City to Houston in October from $135

One-Way flights