Cheapest one-way flights from Houston to Guatemala City in December from $422

AirHint found the following cheapest one-way flights from Houston (HOU) to Guatemala City (GUA) in December 2025 (see full year).

One-Way flights

12 Dec Avianca
12 Dec United direct

Also check the deals for return flights from Houston to Guatemala City in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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