Cheapest one-way flights from Houston to Rio Negro in May from $140

AirHint found the following cheapest one-way flights from Houston (HOU) to Rio Negro (MDE) in May 2026 (see full year).

One-Way flights

31 May Spirit Airlines
26 May Spirit Airlines
01 May Frontier Airlines
12 May Spirit Airlines
17 May Spirit Airlines
14 May Spirit Airlines
20 May Spirit Airlines
09 May Spirit Airlines
29 May Spirit Airlines
12 May United direct

Also check the deals for return flights from Houston to Rio Negro in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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