Cheapest one-way flights from Houston to Panama City in September from $147

AirHint found the following cheapest one-way flights from Houston (HOU) to Panama City (PTY) in September 2025 (see full year).

One-Way flights

28 Sep Spirit Airlines
08 Sep Spirit Airlines
09 Sep Spirit Airlines
13 Sep Spirit Airlines
07 Sep Spirit Airlines
28 Sep United direct
08 Sep United direct
09 Sep United direct
13 Sep United direct
07 Sep United direct

Also check the deals for return flights from Houston to Panama City in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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