Cheapest one-way flights from Jacksonville to Santo Domingo in May from $149

Best time to book flights for Jacksonville (JAX) to Santo Domingo (SDQ) flights at AirHint

AirHint found the following cheapest one-way flights from Jacksonville (JAX) to Santo Domingo (SDQ) in May 2025 (see full year).

One-Way flights

24 May Frontier Airlines

Also check the deals for return flights from Jacksonville to Santo Domingo in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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