Cheapest one-way flights from New York to Santiago in December from $280

AirHint found the following cheapest one-way flights from New York (JFK) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

06 Dec Frontier Airlines
09 Dec Avianca
04 Dec Avianca
07 Dec Frontier Airlines
12 Dec Frontier Airlines
05 Dec Avianca
13 Dec Avianca
14 Dec Avianca
15 Dec Frontier Airlines
24 Dec LATAM Airlines Group

Also check the deals for return flights from New York to Santiago in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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