Cheapest one-way flights from New York to Santiago in December from $225

AirHint found the following cheapest one-way flights from New York (JFK) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

06 Dec Frontier Airlines
02 Dec Frontier Airlines
07 Dec Frontier Airlines
04 Dec Frontier Airlines
15 Dec Frontier Airlines
09 Dec Frontier Airlines
16 Dec Frontier Airlines
31 Dec LATAM Airlines Group
01 Dec Avianca
28 Dec jetBlue

Also check the deals for return flights from New York to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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