Cheapest one-way flights from Los Angeles to Santiago in December from $309

AirHint found the following cheapest one-way flights from Los Angeles (LAX) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

03 Dec Spirit Airlines
02 Dec Volaris
04 Dec Spirit Airlines
09 Dec Spirit Airlines
07 Dec Spirit Airlines
06 Dec LATAM Airlines Group
28 Dec LATAM Airlines Group
01 Dec Volaris
09 Dec LATAM Airlines Group direct
02 Dec LATAM Airlines Group direct

Also check the deals for return flights from Los Angeles to Santiago in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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