Cheapest one-way flights from New York to Santiago in December from $253

AirHint found the following cheapest one-way flights from New York (LGA) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

11 Dec Spirit Airlines
09 Dec Spirit Airlines
05 Dec Spirit Airlines
13 Dec Spirit Airlines
12 Dec Spirit Airlines
29 Dec Air Canada
16 Dec Spirit Airlines
28 Dec LATAM Airlines Group
22 Dec LATAM Airlines Group
25 Dec United

Also check the deals for return flights from New York to Santiago in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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