Cheapest one-way flights from Madrid to Brussels in November from $45

Best time to book flights for Madrid (MAD) to Brussels (BRU) flights at AirHint

AirHint found the following cheapest one-way flights from Madrid (MAD) to Brussels (BRU) in November 2025 (see full year).

One-Way flights

06 Nov Iberia direct
20 Nov Ryanair direct
27 Nov Ryanair direct
13 Nov Ryanair direct
15 Nov Ryanair direct
08 Nov Ryanair direct
05 Nov Air Europa direct
12 Nov Iberia
04 Nov Iberia direct
12 Nov Ryanair direct

Also check the deals for return flights from Madrid to Brussels in November.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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