Cheapest one-way flights from Madrid to Rome in April from $38

AirHint found the following cheapest one-way flights from Madrid (MAD) to Rome (FCO) in April 2026 (see full year).

One-Way flights

04 Apr Ryanair direct
05 Apr Ryanair direct
14 Apr ITA Airways direct
26 Apr ITA Airways direct
17 Apr ITA Airways direct
20 Apr Iberia direct
09 Apr Iberia direct
23 Apr Iberia direct
11 Apr Iberia direct
03 Apr Wizz Air Malta direct

Also check the deals for return flights from Madrid to Rome in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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