Cheapest one-way flights from Madrid to Sao Paulo in October from $452

AirHint found the following cheapest one-way flights from Madrid (MAD) to Sao Paulo (GRU) in October 2025 (see full year).

One-Way flights

24 Oct Royal Air Maroc
31 Oct Royal Air Maroc
10 Oct Royal Air Maroc
11 Oct Royal Air Maroc
01 Oct Royal Air Maroc
25 Oct Royal Air Maroc
09 Oct Royal Air Maroc
26 Oct Royal Air Maroc
27 Oct Royal Air Maroc
22 Oct TAP

Also check the deals for return flights from Madrid to Sao Paulo in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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