Cheapest one-way flights from Madrid to Sao Paulo in September from $306

Best time to book flights for Madrid (MAD) to Sao Paulo (GRU) flights at AirHint

AirHint found the following cheapest one-way flights from Madrid (MAD) to Sao Paulo (GRU) in September 2025 (see full year).

One-Way flights

06 Sep Iberia direct
09 Sep Iberia direct
04 Sep Iberia direct
07 Sep Iberia direct
11 Sep Iberia direct
12 Sep Iberia direct
03 Sep Iberia direct
02 Sep Iberia direct
05 Sep Iberia direct
08 Sep Iberia direct

Also check the deals for return flights from Madrid to Sao Paulo in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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