Cheapest one-way flights from Madrid to Panama City in January from $363

AirHint found the following cheapest one-way flights from Madrid (MAD) to Panama City (PTY) in January 2026 (see full year).

One-Way flights

26 Jan Avianca
05 Jan Avianca
16 Jan Air Europa direct
26 Jan Air Europa direct
11 Jan TAP
10 Jan Air Europa direct
05 Jan Air Europa direct
11 Jan Air Europa direct

Also check the deals for return flights from Madrid to Panama City in January.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City

Feel free to contact us with any feedback or request another flight research.