Cheapest one-way flights from Madrid to Panama City in February from $343

AirHint found the following cheapest one-way flights from Madrid (MAD) to Panama City (PTY) in February 2026 (see full year).

One-Way flights

05 Feb Avianca
21 Feb Avianca
13 Feb Avianca
01 Feb Avianca
05 Feb Air Europa direct
04 Feb Air Europa direct
21 Feb Air Europa direct
13 Feb Air Europa direct
01 Feb Air Europa direct

Also check the deals for return flights from Madrid to Panama City in February.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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