Cheapest one-way flights from Madrid to Santiago in May from $475

AirHint found the following cheapest one-way flights from Madrid (MAD) to Santiago (SCL) in May 2026 (see full year).

One-Way flights

14 May Azul Airlines
13 May Iberia
08 May Air Europa
02 May LATAM Airlines Group direct
08 May LATAM Airlines Group direct
04 May LATAM Airlines Group direct
14 May LATAM Airlines Group direct
21 May LATAM Airlines Group direct
23 May Iberia
23 May LATAM Airlines Group direct

Also check the deals for return flights from Madrid to Santiago in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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