Cheapest one-way flights from Madrid to Santa Cruz in April from $417

AirHint found the following cheapest one-way flights from Madrid (MAD) to Santa Cruz (VVI) in April 2026 (see full year).

One-Way flights

24 Apr Avianca
15 Apr Avianca
27 Apr Avianca
18 Apr Avianca
18 Apr Air Europa direct
27 Apr Air Europa direct
24 Apr Boliviana de Aviacion direct
15 Apr Boliviana de Aviacion direct
03 Apr Boliviana de Aviacion direct
01 Apr Iberia direct

Also check the deals for return flights from Madrid to Santa Cruz in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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