Cheapest one-way flights from Chicago to Rome in May from $452

AirHint found the following cheapest one-way flights from Chicago (MDW) to Rome (FCO) in May 2026 (see full year).

One-Way flights

08 May Porter Airlines (Canada) Ltd
29 May Porter Airlines (Canada) Ltd
30 May Porter Airlines (Canada) Ltd
22 May Porter Airlines (Canada) Ltd
17 May Delta
31 May Air France
09 May Air France
13 May Air France
26 May Porter Airlines (Canada) Ltd

Also check the deals for return flights from Chicago to Rome in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rome

Cheap car rent in Rome

Feel free to contact us with any feedback or request another flight research.