Cheapest one-way flights from Chicago to Rome in May from $447

Best time to book flights for Chicago (MDW) to Rome (FCO) flights at AirHint

AirHint found the following cheapest one-way flights from Chicago (MDW) to Rome (FCO) in May 2025 (see full year).

One-Way flights

12 May Frontier Airlines
30 May Porter Airlines (Canada) Ltd
31 May Porter Airlines (Canada) Ltd
08 May Frontier Airlines
15 May Frontier Airlines
16 May Frontier Airlines
18 May Frontier Airlines
14 May KLM
24 May Porter Airlines (Canada) Ltd
09 May Air France

Also check the deals for return flights from Chicago to Rome in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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