Cheapest one-way flights from Chicago to Rome in September from $484
AirHint found the following cheapest one-way flights from Chicago (MDW) to Rome (FCO) in September 2025 (see full year).
One-Way flights
| 07 Sep | Frontier Airlines | ||
| 21 Sep | Frontier Airlines | ||
| 25 Sep | Air Transat | ||
| 26 Sep | Air Transat | ||
| 09 Sep | Air France | ||
| 10 Sep | KLM | ||
| 30 Sep | Air France | ||
| 15 Sep | KLM | ||
| 08 Sep | Delta | ||
| 20 Sep | Air France |
Also check the deals for return flights from Chicago to Rome in September.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
