AirHint found the following cheapest one-way flights from Chicago (MDW) to Lisbon (LIS) in December 2025 (see full year).
One-Way flights
| 07 Dec | Frontier Airlines | ||
| 12 Dec | Virgin Atlantic | ||
| 31 Dec | Frontier Airlines | ||
| 30 Dec | Virgin Atlantic | ||
| 19 Dec | Frontier Airlines |
Also check the deals for return flights from Chicago to Lisbon in December.
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