Cheapest one-way flights from Chicago to Rio Negro in December from $214

AirHint found the following cheapest one-way flights from Chicago (MDW) to Rio Negro (MDE) in December 2025 (see full year).

One-Way flights

15 Dec Frontier Airlines
13 Dec Frontier Airlines
24 Dec Frontier Airlines
30 Dec Frontier Airlines
09 Dec Frontier Airlines
08 Dec Frontier Airlines
22 Dec Frontier Airlines
04 Dec Frontier Airlines
23 Dec Frontier Airlines
06 Dec Frontier Airlines

Also check the deals for return flights from Chicago to Rio Negro in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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