Cheapest one-way flights from Melbourne to Santiago in October from $1214

Best time to book flights for Melbourne (MEL) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest one-way flights from Melbourne (MEL) to Santiago (SCL) in October 2025 (see full year).

One-Way flights

06 Oct LATAM Airlines Group direct
15 Oct LATAM Airlines Group direct
20 Oct LATAM Airlines Group direct
22 Oct LATAM Airlines Group direct
25 Oct LATAM Airlines Group direct
08 Oct LATAM Airlines Group direct
19 Oct Jetstar
21 Oct LATAM Airlines Group
26 Oct LATAM Airlines Group
09 Oct LATAM Airlines Group

Also check the deals for return flights from Melbourne to Santiago in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago