Cheapest one-way flights from Mexico City to Sao Paulo in December from $209

AirHint found the following cheapest one-way flights from Mexico City (MEX) to Sao Paulo (GRU) in December 2025 (see full year).

One-Way flights

06 Dec Arajet
24 Dec Arajet
23 Dec Volaris
26 Dec Copa
30 Dec Copa
30 Dec LATAM Airlines Group direct
23 Dec LATAM Airlines Group direct
24 Dec LATAM Airlines Group direct
06 Dec LATAM Airlines Group direct
26 Dec LATAM Airlines Group direct

Also check the deals for return flights from Mexico City to Sao Paulo in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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