AirHint found the following cheapest one-way flights from Mexico City (MEX) to Madrid (MAD) in April 2026 (see full year).

One-Way flights

08 Apr	Iberia	direct
21 Apr	Iberia	direct
19 Apr	Iberia	direct
26 Apr	Iberia	direct
29 Apr	Iberia	direct
22 Apr	Iberia	direct
07 Apr	Iberia	direct
14 Apr	Iberia	direct
28 Apr	Iberia	direct
13 Apr	Iberia	direct

Also check the deals for return flights from Mexico City to Madrid in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Mexico City to Madrid in April from $407

One-Way flights