Cheapest one-way flights from Mexico City to Santo Domingo in December from $156

AirHint found the following cheapest one-way flights from Mexico City (MEX) to Santo Domingo (SDQ) in December 2025 (see full year).

One-Way flights

10 Dec Arajet direct
03 Dec Arajet direct
17 Dec Arajet direct
22 Dec Arajet direct

Also check the deals for return flights from Mexico City to Santo Domingo in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santo Domingo

Cheap car rent in Santo Domingo

Feel free to contact us with any feedback or request another flight research.