AirHint found the following cheapest one-way flights from Montevideo (MVD) to Santiago (SCL) in October 2025 (see full year).

One-Way flights

16 Oct	Sky Airline	direct
27 Oct	Sky Airline	direct
03 Oct	Sky Airline	direct
05 Oct	Sky Airline	direct
25 Oct	Sky Airline	direct
15 Oct	Sky Airline	direct
22 Oct	Sky Airline	direct
07 Oct	Sky Airline	direct
04 Oct	Sky Airline	direct
11 Oct	Sky Airline	direct

Also check the deals for return flights from Montevideo to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Montevideo to Santiago in October from $111

One-Way flights