AirHint found the following cheapest one-way flights from Montevideo (MVD) to Santiago (SCL) in September 2025 (see full year).

One-Way flights

26 Sep	Sky Airline	direct
08 Sep	Sky Airline	direct
28 Sep	Sky Airline	direct
10 Sep	Sky Airline	direct
27 Sep	Sky Airline	direct
29 Sep	Sky Airline	direct
09 Sep	LATAM Airlines Group	direct
05 Sep	Sky Airline	direct
14 Sep	JetSmart
07 Sep	JetSmart

Also check the deals for return flights from Montevideo to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Montevideo to Santiago in September from $119

One-Way flights