Cheapest one-way flights from New York to Santiago in September from $272

AirHint found the following cheapest one-way flights from New York (NYC) to Santiago (SCL) in September 2025 (see full year).

One-Way flights

15 Sep Frontier Airlines
17 Sep Spirit Airlines
11 Sep Spirit Airlines
28 Sep Frontier Airlines
27 Sep Spirit Airlines
14 Sep Spirit Airlines
10 Sep Frontier Airlines
23 Sep Spirit Airlines
26 Sep Spirit Airlines
05 Sep Avianca

Also check the deals for return flights from New York to Santiago in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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